An Apparatus for the Measurement of Pulmonary Function in Unanesthetized Small Animals

Because of public and political opinion, rising costs, and regulations, the use of some types of laboratory animals has been limited. As a result, small mammals - in particular, white rats - have become an acceptable alternative to canines for use in toxicological testing. In this report, a method i...

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Bibliographische Detailangaben
1. Verfasser:	Farrand,R L
Format:	Report
Sprache:	eng
Schlagworte:	Anatomy and Physiology Animal Husbandry and Veterinary Medicine AS553 Calibration Exposure(Physiology) Guinea pigs Inhalation Laboratory animals Laboratory equipment Medical Facilities, Equipment and Supplies Medicine and Medical Research PE62706A Plethysmography Pressure transducers Pulmonary function Rats Respiratory system Test methods
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Beschreibung
Zusammenfassung:	Because of public and political opinion, rising costs, and regulations, the use of some types of laboratory animals has been limited. As a result, small mammals - in particular, white rats - have become an acceptable alternative to canines for use in toxicological testing. In this report, a method is described by which unanesthetized and comfortably restrained rats are exposed by inhalation to yield fairly complete pulmonary information.