Dermal Sensitization Potential of Candidate Insect Repellents: LAIR Formulation (CHF1) N-(n-octyl) glutarimide (CHR2) N-(n-hexyl) glutarimide (CHR3) (E) 1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl)quinoline (CHR5) 1,2,3,4-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl) quinoline (CHR6)

Dermal Sensitization Potential of Candidate Insect Repellents: LAIR Formulation (CHF1) N-(n-octyl) glutarimide (CHR2) N-(n-hexyl) glutarimide (CHR3) (E) 1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl)quinoline (CHR5) 1,2,3,4-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl) quinoline (CHR6)

Arthropods represent a potential disease threat to U.S. Military Forces; consequently, a program to develop improved insect repellents was developed. The dermal sensitization potential of candidate insect repellents was determined using guinea pigs. Test substances CHF1, CHR2, and CHR3 were clearly...

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Hauptverfasser: Fruin,John T, Hanes,Martha A, Black,Kenneth, Gildengorin,Virginia L
Format: Report
Sprache:eng
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AS871
Glutarimides
Guinea pigs
Insect repellents
Molecular structure
PE62770A
Quinolines
Sensitivity
Skin tests
Skin(Anatomy)
Toxicity
Toxicology
WU207
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creator Fruin,John T
Hanes,Martha A
Black,Kenneth
Gildengorin,Virginia L
description Arthropods represent a potential disease threat to U.S. Military Forces; consequently, a program to develop improved insect repellents was developed. The dermal sensitization potential of candidate insect repellents was determined using guinea pigs. Test substances CHF1, CHR2, and CHR3 were clearly non-sensitizing. CHR5 and CHR6 were irritating, possibly sensitizing, and should be retested. (Author)
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The dermal sensitization potential of candidate insect repellents was determined using guinea pigs. Test substances CHF1, CHR2, and CHR3 were clearly non-sensitizing. CHR5 and CHR6 were irritating, possibly sensitizing, and should be retested. (Author)</abstract><oa>free_for_read</oa></addata></record>
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source DTIC Technical Reports
subjects AS871
Glutarimides
Guinea pigs
Insect repellents
Molecular structure
PE62770A
Quinolines
Sensitivity
Skin tests
Skin(Anatomy)
Toxicity
Toxicology
WU207
title Dermal Sensitization Potential of Candidate Insect Repellents: LAIR Formulation (CHF1) N-(n-octyl) glutarimide (CHR2) N-(n-hexyl) glutarimide (CHR3) (E) 1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl)quinoline (CHR5) 1,2,3,4-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl) quinoline (CHR6)
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