Development of Analytical Techniques for Toxicokinetic Research

Development of Analytical Techniques for Toxicokinetic Research

This report describes the methods developed for the analysis of monomethylhydrazine (MMH) and its metabolites in the urine and blood of laboratory rats which had been injected with MMH at concentrations of 7.5 mg/kg and 15 mg/kg. Modifications of this method to analyze for free MMH in urine and bloo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hershey, Mary K, Sherman, Paul L, Pustinger, John V
Format: Report
Sprache:eng
Schlagworte:
BLOOD ANALYSIS
CHEMICAL ANALYSIS
DETERMINATION
GAS CHROMATOGRAPHY
LABORATORY ANIMALS
MASS SPECTROMETRY
METABOLISM
METABOLITES
METHYL HYDRAZINES
PE62202F
RATS
TOXICITY
Toxicology
URINE
WUAMRL63020216
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Beschreibung
Zusammenfassung:This report describes the methods developed for the analysis of monomethylhydrazine (MMH) and its metabolites in the urine and blood of laboratory rats which had been injected with MMH at concentrations of 7.5 mg/kg and 15 mg/kg. Modifications of this method to analyze for free MMH in urine and blood of human origin are also discussed.