Effect of Inflammatory and Noninflammatory Stress on Beta-Hydroxybutyrate and Free Fatty Acids in Rat Blood

Beta-Hydroxybutyrate and free fatty acid concentrations in rat blood were measured during a variety of inflammatory and noninflammatory stresses. Inflammatory stresses included infection with Streptococcus pneumoniae, endotoxemia and induced turpentine abscess. Noninflammatory stresses included fast...

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Hauptverfasser: Neufeld,Harold A, Kaminski,Mitchell V , Jr, Pace,Judith A
Format: Report
Sprache:eng
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Zusammenfassung:Beta-Hydroxybutyrate and free fatty acid concentrations in rat blood were measured during a variety of inflammatory and noninflammatory stresses. Inflammatory stresses included infection with Streptococcus pneumoniae, endotoxemia and induced turpentine abscess. Noninflammatory stresses included fasting plus screen-restraint and fasting plus femoral fracture. Inflammatory stresses caused a marked inhibition of the normal fasting-induced ketosis and a reduction in the level of circulating free fatty acids. Noninflammatory stresses caused no inhibition of the normal fasting-induced ketosis but did cause a reduction in the level of circulating free fatty acids. (Author)