Comparison of Combat Gauze with Fibrin Sealant Patch in Hemorrhage Control after Vascular or Hepatic Trauma

Noncompressible vascular injury not amenable to the use of a tourniquet remains a significant cause of potentially preventable death on the battlefield. The recent development of fibrin patches, which combine both biologic and nonbiologic hemostatic agents, provides a potential adjunct to the curren...

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Hauptverfasser: Pritts,Timothy A, Athota,Krishna P, Goodman,Michael D, Makley,Amy T, Mahoney,Eric, Stevens-Topie,Sabre, Veile,Rose, Heyl,Judy, Cox,Daniel
Format: Report
Sprache:eng
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Zusammenfassung:Noncompressible vascular injury not amenable to the use of a tourniquet remains a significant cause of potentially preventable death on the battlefield. The recent development of fibrin patches, which combine both biologic and nonbiologic hemostatic agents, provides a potential adjunct to the current guidelines for the treatment of these injuries. We examined the effectiveness of a fibrin patch (FP) in comparison to the current standard of Combat Gauze (CG) in an established junctional hemorrhage model. Yorkshire pigs (n=15) were placed under general anesthesia and underwent arterial and venous line placement followed by right femoral vessel exposure. Four pigs were used as controls and underwent line placement and groin incision only. In the remaining 11 pigs, junctional femoral artery hemorrhage was created with a 6-mm aortic punch.