Activation of Mitogen-Activated Protein Kinases and Cyclic AMP Response Element-Binding Protein in Synaptic Plasticity
Current evidence supports a critical role for cAMP in synaptic plasticity. Forskolin increases adenylyl cyclase activity to generate cAMP which induces a long-lasting potentiation of excitatory post synaptic potentials in the hippocampal dentate gyrus to 137 plus or equal to 5% of control, which per...
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| creator | Voulalas,Pamela J |
| description | Current evidence supports a critical role for cAMP in synaptic plasticity. Forskolin increases adenylyl cyclase activity to generate cAMP which induces a long-lasting potentiation of excitatory post synaptic potentials in the hippocampal dentate gyrus to 137 plus or equal to 5% of control, which persists for at least 60 min after forskolin removal.. |
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| subjects | calcium cells(biology) kinases Medicine and Medical Research proteins |
| title | Activation of Mitogen-Activated Protein Kinases and Cyclic AMP Response Element-Binding Protein in Synaptic Plasticity |
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