Cytoplasmatic Alkaline Phosphatase and Allergic Alteration of Blood Leukocytes after Sensitization during Sonne Keratoconjunctivitis in Animals and during Dysentery in Humans

Working on the basis of the pathogenetic significance of bacterial sensitization during dysenteric infection, the authors investigated allergic alterations of leukocytes. They determined the nature of changes and distribution of the activity of cytoplasmatic alkaline phosphatase in the process of allergic alteration of the leukocytes of the blood during Sonne dysenteric keratoconjunctivitis in guinea pigs. They also compared the content and activity of the enzyme in healthy humans, patients with dysentery, and persons excreting bacteria during epidemiological examinations at sites of intestinal infections. A summary of the results is reported. Edited trans. of Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii (USSR) n3 p78-83 1971, by Dean F. W. Koolbeck.