Sickledex Test for S Hemoglobin: A Critique

When the reagents, reactions, and principles of the Sickledex test are understood in terms of modern molecular biology, it is believed that the Sickledex test can be an invaluable and productive tool in the discovery not only of hemoglobin S but other hemoglobinopathies as well, provided: (1) certai...

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Hauptverfasser: Nalbandian,Robert M, Henry,Raymond L, Lusher,Jeanne M, Camp,Frank R , Jr, Conte,Nicholas F
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Henry,Raymond L
Lusher,Jeanne M
Camp,Frank R , Jr
Conte,Nicholas F
description When the reagents, reactions, and principles of the Sickledex test are understood in terms of modern molecular biology, it is believed that the Sickledex test can be an invaluable and productive tool in the discovery not only of hemoglobin S but other hemoglobinopathies as well, provided: (1) certain pitfalls of false positive and false negative reactions are recognized; (2) urea is used to modify the test; and (3) all positive Sickledex specimens are subsequently studied by hemoglobin electrophoresis technique. (Author)
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subjects ANEMIAS
BLOOD DISEASES
DETECTION
DIAGNOSIS(GENERAL)
EFFICIENCY
HEMOGLOBIN
Medicine and Medical Research
SICKLE CELL ANEMIA
TEST METHODS
UREA
title Sickledex Test for S Hemoglobin: A Critique
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