Sickledex Test for S Hemoglobin: A Critique
When the reagents, reactions, and principles of the Sickledex test are understood in terms of modern molecular biology, it is believed that the Sickledex test can be an invaluable and productive tool in the discovery not only of hemoglobin S but other hemoglobinopathies as well, provided: (1) certai...
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| Zusammenfassung: | When the reagents, reactions, and principles of the Sickledex test are understood in terms of modern molecular biology, it is believed that the Sickledex test can be an invaluable and productive tool in the discovery not only of hemoglobin S but other hemoglobinopathies as well, provided: (1) certain pitfalls of false positive and false negative reactions are recognized; (2) urea is used to modify the test; and (3) all positive Sickledex specimens are subsequently studied by hemoglobin electrophoresis technique. (Author) |
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