IN VIVO DEGRADATION OF RADIOACTIVE C14 BUTYL CYANOACRYLATES IN RATS (30 DAYS)

N-Butyl-2-cyanoacrylate is another of the family of cyanoacrylate tissue adhesives. It has proven to be as good an adhesive as methyl-2-cyanoacrylate, but much less histotoxic. It is known that methyl-2-cyano-acrylate is completely degraded in the rat and excreted via the urine, feces, and probably...

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Bibliographische Detailangaben
Hauptverfasser:	Pani,K. C, Gladieux,Gary, Lange,Harold
Format:	Report
Sprache:	eng
Schlagworte:	ACRYLIC RESINS ADHESIVES Adhesives, Seals and Binders Anatomy and Physiology CYANOACRYLATES DEGRADATION ESTERS EXCRETION IN VIVO ANALYSIS Medical Facilities, Equipment and Supplies METABOLISM NITRILES RADIOACTIVE ISOTOPES SURGICAL IMPLANTATION TISSUE ADHESIVES TISSUES(BIOLOGY) TRACER STUDIES
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Beschreibung
Zusammenfassung:	N-Butyl-2-cyanoacrylate is another of the family of cyanoacrylate tissue adhesives. It has proven to be as good an adhesive as methyl-2-cyanoacrylate, but much less histotoxic. It is known that methyl-2-cyano-acrylate is completely degraded in the rat and excreted via the urine, feces, and probably the lungs. This study is designed to investigate the manner and extent to which butyl-2-cyanoacrylate is degraded and excreted from rat implant sites. (Author)