Effects of Salmonella Typhimurium Infection on the Gut Microbiota of Cherry Valley Meat Ducks

infection causes serious economic losses, threatens food safety, and is one of the most important diseases threatening meat duck farming. The gut microbiome is critical in providing resistance against colonization by exogenous microorganisms. Studying the relationship between and gut microbiota can help us better understand the threat of the pathogenic mechanism of and provide a more scientific theoretical basis for its prevention and treatment. This study uses Typhimurium as the research object and Cherry Valley meat duck as the model with which to study the impact of infection on ducks. In this field trial, 2 × 10 CFUs Typhimurium were administered to 3-day-old ducks. After infection, duck viscera were collected to detect the colonization of , and cecal contents were collected to analyze the changes in gut microbiota. The results show that Typhimurium can colonize ducks three days after infection and alter the gut microbiota composition, mainly by increasing the abundance of and . In conclusion, Typhimurium infection significantly alters the intestinal microbiota of ducks and poses a serious public health risk.