Severe autogenously fecal peritonitis in ageing Wistar rats. Response to intravenous meropenem

To evaluate the treatment outcome of severe peritonitis in rats with increasing age. Thirty Wistar rats stratified in three groups: group I - six month-old; group II - 12 month-old; and group III - 18 month-old, underwent autogenously fecal peritonitis (6 ml/kg rat), and were treated with intravenou...

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Veröffentlicht in:	Acta cirurgica brasileira 2014-09, Vol.29 (9), p.615-621
Hauptverfasser:	Mascena, Guilherme Veras, Melo, Maria Cecília Santos Cavalcanti, Gadelha, Diego Nery Benevides, Oliveira, Thárcia Kiara Beserra, Brandt, Carlos Teixeira
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Age Factors Animals Anti-Bacterial Agents - therapeutic use Carbapenems Feces Peritonitis Peritonitis - drug therapy Peritonitis - mortality Peritonitis - pathology Rats Rats, Wistar Reproducibility of Results Risk Factors Sepsis - drug therapy Severity of Illness Index Therapy Thienamycins - therapeutic use Time Factors Treatment Outcome
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Zusammenfassung:	To evaluate the treatment outcome of severe peritonitis in rats with increasing age. Thirty Wistar rats stratified in three groups: group I - six month-old; group II - 12 month-old; and group III - 18 month-old, underwent autogenously fecal peritonitis (6 ml/kg rat), and were treated with intravenous meropenem. The survival animals were followed-up for 45 days. The variables were expressed by their mean and standard error of the mean (SEM). p
ISSN:	0102-8650 1678-2674 0102-8650
DOI:	10.1590/S0102-8650201400150010