Future strategies to improve short- and long-term outcomes of renal transplantation in dogs

Transplants for cats with naturally occurring renal disease have been introduced into clinical practice, but canine renal transplantation represents a greater challenge because of the lack of a balanced immunosuppressive protocol, difficulty in selecting compatible canine kidney donors, and absence...

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Veröffentlicht in:Ciência rural 2021-01, Vol.51 (1)
Hauptverfasser: Braz, Larissa Ayane do Nascimento, Maia, Suellen Rodrigues, Faria, Luciano Alves, Alvarenga, Alef Winter Oliveira, Fernandes, André Luiz Sampaio, Rocha, Guilherme Lages Savassi, Crivellenti, Leandro Zuccolotto
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Sprache:eng ; por
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Zusammenfassung:Transplants for cats with naturally occurring renal disease have been introduced into clinical practice, but canine renal transplantation represents a greater challenge because of the lack of a balanced immunosuppressive protocol, difficulty in selecting compatible canine kidney donors, and absence of transplantation monitoring protocols. This and other important factors will be discussed in this review to help improve short- and long-term outcomes for renal transplantation in dogs. RESUMO: O transplante renal em gatos com doença renal naturalmente adquirida está cada vez mais sendo introduzido na prática clínica. O transplante renal em cães, por sua vez, representa um desafio maior devido a falta da definição de um protocolo imunossupressor equilibrado, dificuldade na seleção de doadores compatíveis e ausência de protocolos de monitoramento de transplantes. Esses e outros fatores serão abordados nesta revisão afim de melhorar os resultados, tanto a curto quanto a longo prazo do transplante renal em cães.
ISSN:0103-8478
1678-4596
1678-4596
DOI:10.1590/0103-8478cr20200025