Impact of inflammation on cognitive function in patients with highly inflammatory rheumatoid arthritis

ObjectiveTo evaluate cognitive function in patients with rheumatoid arthritis (RA) and inflammatory activity.Patients and methodsWe performed a cross-sectional study of a cohort of patients with RA initiating their first biological treatment due to moderate-to-high inflammation and a healthy control...

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Veröffentlicht in:	Rheumatic & musculoskeletal diseases open 2024-07, Vol.10 (2), p.e004422
Hauptverfasser:	Mena-Vázquez, Natalia, Ortiz-Márquez, Fernando, Ramírez-García, Teresa, Cabezudo-García, Pablo, García-Studer, Aimara, Mucientes-Ruiz, Arkaitz, Lisbona-Montañez, Jose Manuel, Borregón-Garrido, Paula, Ruiz-Limón, Patricia, Redondo-Rodríguez, Rocío, Manrique-Arija, Sara, Cano-García, Laura, Serrano-Castro, Pedro J., Fernández-Nebro, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anxiety Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - complications Arthritis, Rheumatoid - psychology Biological Therapy Biomarkers - blood C-Reactive Protein - analysis C-Reactive Protein - metabolism Case-Control Studies Cognition Cognitive ability Cognitive Dysfunction - diagnosis Cognitive Dysfunction - etiology Comorbidity Cross-Sectional Studies Disease Executive function Female Humans Immunotherapy Inflammation Inflammation - blood Inflammation - etiology Interleukin-6 - blood Male Memory Mental depression Metabolic disorders Middle Aged Neuropsychological Tests Neuropsychology Neurosciences Quality of Life Rheumatoid arthritis Rheumatology Severity of Illness Index Tumor necrosis factor-TNF White people
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Beschreibung
Zusammenfassung:	ObjectiveTo evaluate cognitive function in patients with rheumatoid arthritis (RA) and inflammatory activity.Patients and methodsWe performed a cross-sectional study of a cohort of patients with RA initiating their first biological treatment due to moderate-to-high inflammation and a healthy control group (no inflammatory diseases) matched for age, sex and educational level. All participants underwent a comprehensive neuropsychological assessment, with cognitive impairment defined as a Montreal Cognitive Assessment (MoCA) score
ISSN:	2056-5933 2056-5933
DOI:	10.1136/rmdopen-2024-004422