Developing Community Resources for Nucleic Acid Structures

Developing Community Resources for Nucleic Acid Structures

In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has been used to enable research. Plans for the n...

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Veröffentlicht in:Life (Basel, Switzerland) Switzerland), 2022-04, Vol.12 (4), p.540
Hauptverfasser: Berman, Helen M, Lawson, Catherine L, Schneider, Bohdan
Format: Artikel
Sprache:eng
Schlagworte:
Acids
biological structure database
Collaboration
DNA
Flexibility
Hydration
Knowledge bases (artificial intelligence)
Medical research
nucleic acid conformation
nucleic acid structures
Nucleic acids
Proteins
Queries
Review
RNA
Single crystals
Transfer RNA
validation standards
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Zusammenfassung:In this review, we describe the creation of the Nucleic Acid Database (NDB) at Rutgers University and how it became a testbed for the current infrastructure of the RCSB Protein Data Bank. We describe some of the special features of the NDB and how it has been used to enable research. Plans for the next phase as the Nucleic Acid Knowledgebase (NAKB) are summarized.
ISSN:2075-1729
2075-1729
DOI:10.3390/life12040540