Case of Carbapenem-Resistant Salmonella Typhi Infection, Pakistan, 2022

Case of Carbapenem-Resistant Salmonella Typhi Infection, Pakistan, 2022

Salmonella Typhi infection in a patient in Pakistan initially responded to standard treatment but failed to respond to subsequent treatment. The first strain was susceptible to carbapenems and azithromycin; subsequent strains harbored the NDM-5 gene. Treatment with a combination of intravenous merop...

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Veröffentlicht in:Emerging infectious diseases 2023-11, Vol.29 (11), p.2395-2397
Hauptverfasser: Nizamuddin, Summiya, Khan, Ejaz Ahmed, Chattaway, Marie Anne, Godbole, Gauri
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Antibiotics
Antimicrobial agents
antimicrobial resistance
Beta lactamases
carbapenem resistance
Case of Carbapenem-Resistant
Case studies
Diagnosis
Down syndrome
Drug resistance
Drug therapy
Fever
Genomes
Health aspects
Hospitals
Imipenem
Infection
Infections
Leukocytes
Medical research
Research Letter
Salmonella
Salmonella enteria serovar Typhi
Salmonella food poisoning
Salmonella Typhi
Salmonellosis
Tetracycline
Tetracyclines
therapy
Typhi, Pakistan, 2022
Typhoid
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Zusammenfassung:Salmonella Typhi infection in a patient in Pakistan initially responded to standard treatment but failed to respond to subsequent treatment. The first strain was susceptible to carbapenems and azithromycin; subsequent strains harbored the NDM-5 gene. Treatment with a combination of intravenous meropenem and colistin was successful. Carbapenem-resistant Salmonella Typhi emergence will hinder treatment.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2911.230499