A distinct symptom pattern emerges for COVID-19 long-haul: a nationwide study

Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom...

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Veröffentlicht in:Scientific reports 2022-09, Vol.12 (1), p.15905-11, Article 15905
Hauptverfasser: Pinto, Melissa D., Downs, Charles A., Huang, Yong, El-Azab, Sarah A., Ramrakhiani, Nathan S., Barisano, Anthony, Yu, Lu, Taylor, Kaitlyn, Esperanca, Alvaro, Abrahim, Heather L., Hughes, Thomas, Herrera, Maria Giraldo, Rahamani, Amir M., Dutt, Nikil, Chakraborty, Rana, Mendiola, Christian, Lambert, Natalie
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Sprache:eng
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Zusammenfassung:Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by the persistence of symptoms. The purpose of this cross-sectional study was to identify a distinct and significant temporal pattern of PASC symptoms (symptom type and onset) among a nationwide sample of PASC survivors (n = 5652). The sample was randomly sorted into two independent samples for exploratory (EFA) and confirmatory factor analyses (CFA). Five factors emerged from the EFA: (1) cold and flu-like symptoms, (2) change in smell and/or taste, (3) dyspnea and chest pain, (4) cognitive and visual problems, and (5) cardiac symptoms. The CFA had excellent model fit ( x 2  = 513.721, df = 207, p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-20214-7