Metastatic Triple Negative Breast Cancer: The New Era of Thinking

The heterogeneity of triple negative breast cancer (TNBC) is reflected in a bizarre response to therapy. Although it is chemotherapy sensitive, the failure is the usual pathway either in local or distance status. With progression in Gene Expression Profile (GEP) and other molecular techniques, TNBC...

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Veröffentlicht in:Forum of clinical oncology 2021-05, Vol.12 (1), p.31-38
Hauptverfasser: Mohammed, Amrallah A., Elbassuiony, Mohamed A., Rashied, Hanaa
Format: Artikel
Sprache:eng
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Zusammenfassung:The heterogeneity of triple negative breast cancer (TNBC) is reflected in a bizarre response to therapy. Although it is chemotherapy sensitive, the failure is the usual pathway either in local or distance status. With progression in Gene Expression Profile (GEP) and other molecular techniques, TNBC is divided into sub-types with unique pathways. In the current review, we are trying to highlight based on the molecular classification of TNBC and the management based on every type.
ISSN:1792-362X
1792-362X
DOI:10.2478/fco-2018-0007