Progress of gut-kidney axis in the pathogenesis of crescentic glomerulonephritis

Crescent glomerulonephritis (CreGN) is the most dangerous glomerulonephritis and always leads to end stage renal disease (ESRD). The immunological mechanism plays an important role in its pathogenesis and prognosis. Recently, the role of the gut and intestinal microbiota in a variety of kidney disea...

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Veröffentlicht in:	Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics 2022-04, Vol.42 (4), p.656-660
1. Verfasser:	YIN Huan-huan, SHI Xiao-xiao, CHEN Li-meng
Format:	Artikel
Sprache:	chi
Schlagworte:	gut-kidney axis\|intestinal microbiota\|crescentic glomerulonephritis\|intestinal mucosal immunity\|molecular simulation
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Beschreibung
Zusammenfassung:	Crescent glomerulonephritis (CreGN) is the most dangerous glomerulonephritis and always leads to end stage renal disease (ESRD). The immunological mechanism plays an important role in its pathogenesis and prognosis. Recently, the role of the gut and intestinal microbiota in a variety of kidney diseases including CreGN has been disclosed. The “gut-kidney axis” will directly affect the immune response in the kidney and subsequent pathophysiology through the intestinal microbiota and gut-derived immune cells.
ISSN:	1001-6325
DOI:	10.16352/j.issn.1001-6325.2022.04.016