A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant

A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, who achieved completed morphological remission, and FLT3-itd negativity, following 9 cycles of azacitadine in combination with escalating doses of donor lymphocyte infusions following relapse 18 months...

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Veröffentlicht in:Hematology reports 2019-02, Vol.11 (1), p.7800-7800
Hauptverfasser: Horgan, Claire, Kanellopoulos, Alexandros, Paneesha, Shankara, Kishore, Bhuvan, Lovell, Richard, Nikolousis, Emmanouil
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Sprache:eng
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Zusammenfassung:A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, who achieved completed morphological remission, and FLT3-itd negativity, following 9 cycles of azacitadine in combination with escalating doses of donor lymphocyte infusions following relapse 18 months post reduced intensity HLAA mismatch Campath conditioning allogeneic stem cell transplant.
ISSN:2038-8322
2038-8330
2038-8330
DOI:10.4081/hr.2019.7800