Isolated cold-induced sweating in a young Saudi male: Case report

Cold-induced sweating is a rare condition, which is reported in the literature as part of Crisponi syndrome in which patients have many neurological and skeletal abnormalities. We report a case of isolated nonsyndromic cold-induced sweating in a 24-year-old Saudi male. The patient was treated with many treatments, including clonidine 0.1 mg, amitriptyline, and fluoxetine, but these were discontinued due to side effects. The patient was treated with onabotulinum toxin A with partial satisfactory result. Treatment options for cold-induced sweating are limited, and in this case, inadequate.