Type 2 diabetes and risk of diverticular disease: a Danish cohort study

ObjectivesTo investigate the association between type 2 diabetes and risk of diverticular disease. Unlike previous studies, which have found conflicting results, we aimed to distinguish between diabetes types and adjust for modifiable risk factors.DesignObservational cohort study.SettingPopulation-b...

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Veröffentlicht in:BMJ open 2022-02, Vol.12 (2), p.e059852-e059852
Hauptverfasser: Wittström, Felix, Skajaa, Nils, Bonnesen, Kasper, Pedersen, Lars, Ekholm, Ola, Strate, Lisa, Erichsen, Rune, Sørensen, Henrik Toft
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Sprache:eng
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Zusammenfassung:ObjectivesTo investigate the association between type 2 diabetes and risk of diverticular disease. Unlike previous studies, which have found conflicting results, we aimed to distinguish between diabetes types and adjust for modifiable risk factors.DesignObservational cohort study.SettingPopulation-based Danish medical databases, covering the period 2005–2018.ParticipantsRespondents of the 2010 or the 2013 Danish National Health Survey, of which there were 15 047 patients with type 2 diabetes and 210 606 patients without diabetes.Primary and secondary outcome measuresHazard ratios (HRs) for incident hospital diagnosis of diverticular disease adjusted for survey year, sex, age, body mass index (BMI), physical activity intensity, smoking behaviour, diet and education based on Cox regression analysis. As latency may affect the association between type 2 diabetes and diverticular disease, patients with type 2 diabetes were stratified into those with
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2021-059852