DObesity: Relationship between vitamin D deficiency, obesity and sclerostin as a novel biomarker of bone metabolism

DObesity: Relationship between vitamin D deficiency, obesity and sclerostin as a novel biomarker of bone metabolism

To study the relationship between obesity, insulin resistance, vitamin D deficiency and sclerostin as a bone biomarker. Cross-section study of 75 subjects grouped into 3 groups; obese (n = 31), overweight (n = 23) and normal (n = 21) subjects. Sclerostin, fasting insulin, fasting plasma glucose and...

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Veröffentlicht in:Journal of clinical & translational endocrinology 2019-09, Vol.17, p.100197-100197, Article 100197
Hauptverfasser: Azzam, Eman Zaki, Ata, Mohamed Nabil, Younan, Doreen Nazeih, Salem, Tarek M., Abdul-Aziz, Ahmed Alaa
Format: Artikel
Sprache:eng
Schlagworte:
Bone metabolism
Insulin resistance
Obesity
Research Paper
Sclerostin
Vitamin D
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Zusammenfassung:To study the relationship between obesity, insulin resistance, vitamin D deficiency and sclerostin as a bone biomarker. Cross-section study of 75 subjects grouped into 3 groups; obese (n = 31), overweight (n = 23) and normal (n = 21) subjects. Sclerostin, fasting insulin, fasting plasma glucose and 25(OH)D were measured and anthropometric measures were taken. 25(OH)D was lower in obese subjects than overweight and control groups (mean ± SD 5.27 ± 5.14 vs. 12.55 ± 6.99 vs.17.65 ± 4.07 ng/L, p 
ISSN:2214-6237
2214-6237
DOI:10.1016/j.jcte.2019.100197