Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant Mycoplasma genitalium

Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Emerging infectious diseases 2020-08, Vol.26 (8), p.1870-1874
Hauptverfasser:	Durukan, Duygu, Doyle, Michelle, Murray, Gerald, Bodiyabadu, Kaveesha, Vodstrcil, Lenka, Chow, Eric P F, Jensen, Jorgen S, Fairley, Christopher K, Aguirre, Ivette, Bradshaw, Catriona S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Antibiotics Antimicrobial agents Asymptomatic Care and treatment Combination therapy Dispatch Doxycycline Doxycycline and Sitafloxacin Combination Therapy for Treating Highly Resistant dual-class resistance Failure Health aspects Infection Infections macrolide resistance Microbial drug resistance multidrug resistance Mutation Mycoplasma genitalium Patients Pelvic inflammatory disease quinolone resistance Sexual health Sexually transmitted diseases sexually transmitted infections
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Antimicrobial-resistant Mycoplasma genitalium is becoming increasingly common and creating major treatment challenges. We present early data on combination therapy with doxycycline and sitafloxacin to treat highly resistant M. genitalium. We found the regimen was well tolerated and cured 11/12 infections that had failed prior regimens with moxifloxacin and pristinamycin.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2608.191806