Nomograms predicting cancer-specific survival for stage IV colorectal cancer with synchronous lung metastases
This study aimed to establish a nomogram for the prediction of cancer-specific survival (CSS) of CRC patients with synchronous LM. The final prognostic nomogram based on prognostic factors was evaluated by concordance index (C-index), time-dependent receiver operating characteristic curves, and cali...
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Veröffentlicht in: | Scientific reports 2022-08, Vol.12 (1), p.13952-13952, Article 13952 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | This study aimed to establish a nomogram for the prediction of cancer-specific survival (CSS) of CRC patients with synchronous LM. The final prognostic nomogram based on prognostic factors was evaluated by concordance index (C-index), time-dependent receiver operating characteristic curves, and calibration curves. In the training and validation groups, the C-index for the nomogram was 0.648 and 0.638, and the AUC was 0.793 and 0.785, respectively. The high quality of the calibration curves in the nomogram models for CSS at 1-, 3-, and 5-year was observed. The nomogram model provided a conventional and useful tool to evaluate the 1-, 3-, and 5-year CSS of CRC patients with synchronous LM. |
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ISSN: | 2045-2322 2045-2322 |
DOI: | 10.1038/s41598-022-18258-w |