Curcumin and inflammation in non-alcoholic fatty liver disease: a randomized, placebo controlled clinical trial

The aim of the present study was to evaluate the effects of curcumin supplementation on inflammatory indices, and hepatic features in patients with non-alcoholic fatty liver disease (NAFLD). Fifty patients with NAFLD were randomized to receive lifestyle modification advice plus either 1500 mg curcum...

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Veröffentlicht in:	BMC gastroenterology 2019-07, Vol.19 (1), p.133-133, Article 133
Hauptverfasser:	Saadati, Saeede, Sadeghi, Amir, Mansour, Asieh, Yari, Zahra, Poustchi, Hossein, Hedayati, Mehdi, Hatami, Behzad, Hekmatdoost, Azita
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Care and treatment Curcumin Curcumin - administration & dosage Dietary supplements Fatty liver Female Health aspects Humans Inflammation Inflammation - drug therapy Inflammation - pathology Liver - drug effects Liver - pathology Liver Function Tests - methods Male Middle Aged NAFLD NASH NF-kappa B - analysis Non-alcoholic Fatty Liver Disease - blood Non-alcoholic Fatty Liver Disease - pathology Non-alcoholic Fatty Liver Disease - psychology Non-alcoholic Fatty Liver Disease - therapy Risk Reduction Behavior Testing Treatment Outcome Tumor Necrosis Factor-alpha - analysis Turmeric
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Zusammenfassung:	The aim of the present study was to evaluate the effects of curcumin supplementation on inflammatory indices, and hepatic features in patients with non-alcoholic fatty liver disease (NAFLD). Fifty patients with NAFLD were randomized to receive lifestyle modification advice plus either 1500 mg curcumin or the same amount of placebo for 12 weeks. Curcumin supplementation was associated with significant decrease in hepatic fibrosis (p
ISSN:	1471-230X 1471-230X
DOI:	10.1186/s12876-019-1055-4