Synthesis and Characterization of New Diketone Analogues of Podophyllotoxin
The new compounds 6,6a‐dihydro‐2,3‐dimethoxy‐9‐nitro–11bH benzo [C]‐fluoren 5,7‐dione, 6,6a‐dihydro‐2,3‐dimethoxy‐9‐chloro–11bH benzo[C]‐fluoren‐5,7‐dione and 6,6a‐dihydro‐2,3‐dimethoxy‐9‐fluoro–11bH benzo[C]‐fluoren‐5,7‐ dione were synthesized in high yields. They are analogues of naturally occurri...
Gespeichert in:
| Veröffentlicht in: | E-journal of chemistry 2008-01, Vol.5 (1), p.114-119 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The new compounds 6,6a‐dihydro‐2,3‐dimethoxy‐9‐nitro–11bH benzo [C]‐fluoren 5,7‐dione, 6,6a‐dihydro‐2,3‐dimethoxy‐9‐chloro–11bH benzo[C]‐fluoren‐5,7‐dione and 6,6a‐dihydro‐2,3‐dimethoxy‐9‐fluoro–11bH benzo[C]‐fluoren‐5,7‐ dione were synthesized in high yields. They are analogues of naturally occurring lignan podophyllotoxin which exhibits anticancer activity. They are very essential to study anticancer activity. |
|---|---|
| ISSN: | 2090-9063 0973-4945 2090-9071 2090-9810 |
| DOI: | 10.1155/2008/314724 |