Exploring cost reduction strategies for serum free media development

Cultivated meat production offers solutions in addressing global food security and sustainability challenges. However, serum-free media (SFM) used in cultivating the cells are expensive, contributing to at least 50% of variable operating costs. This review explores technologies for cost-effective SF...

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Veröffentlicht in:	NPJ science of food 2024-12, Vol.8 (1), p.107-10, Article 107
Hauptverfasser:	Quek, Jun Ping, Gaffoor, Azra Anwar, Tan, Yu Xuan, Tan, Tessa Rui Min, Chua, Yu Feng, Leong, Dawn Sow Zong, Ali, Alif Sufiyan, Ng, Say Kong
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337 631/45 631/61 631/80 Cell growth Chemistry Chemistry and Materials Science Chemistry/Food Science Culture media Cultured meat Design of experiments Fibroblasts Food Food Microbiology Food Science Food security Growth factors Insulin Meat industry Meat production Metabolism Metabolites Nutrition Operating costs Proteins Raw materials Regulatory approval Review Selenium Serum-free medium
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Zusammenfassung:	Cultivated meat production offers solutions in addressing global food security and sustainability challenges. However, serum-free media (SFM) used in cultivating the cells are expensive, contributing to at least 50% of variable operating costs. This review explores technologies for cost-effective SFM, focusing on reducing cost from using growth factors and recombinant proteins, using affordable raw materials for basal media, and implementing cost-saving measures like media recycling and reducing waste build-up.
ISSN:	2396-8370 2396-8370
DOI:	10.1038/s41538-024-00352-0