Sarcoma Patients Admitted to the Intensive Care Unit (ICU): Predictive Relevance of Common Sepsis and Performance Parameters

Prognosis of sarcoma patients is improving, with a better understanding of sarcomagenesis revealing novel therapeutic targets. However, aggressive chemotherapy remains an essential part of treatment, bearing the risk of severe side effects that require intensive medical treatment. Available data on...

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Veröffentlicht in:Cancer management and research 2023-01, Vol.15, p.321-334
Hauptverfasser: Striefler, Jana K, Binder, Phung T, Brandes, Franziska, Rau, Daniel, Wittenberg, Silvan, Kaul, David, Roohani, Siyer, Jarosch, Armin, Schäfer, Frederik M, Öllinger, Robert, Märdian, Sven, Bullinger, Lars, Eckardt, Kai-Uwe, Kruse, Jan, Flörcken, Anne
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Sprache:eng
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Zusammenfassung:Prognosis of sarcoma patients is improving, with a better understanding of sarcomagenesis revealing novel therapeutic targets. However, aggressive chemotherapy remains an essential part of treatment, bearing the risk of severe side effects that require intensive medical treatment. Available data on the characteristics and clinical outcome of sarcoma patients admitted to intensive care units (ICU) are sparse. We performed a retrospective analysis of sarcoma patients admitted to the ICU from 2005 to 2022. Patients ≥18 years with histologically proven sarcoma were included in our study. Sixty-six patients were eligible for analysis. The following characteristics had significant impact on overall survival: sex (p=0.046), tumour localization (p=0.02), therapeutic intention (p=0.02), line of chemotherapy (p
ISSN:1179-1322
1179-1322
DOI:10.2147/CMAR.S400430