Preparation and characterization of polymer blend and Nano composite materials based on PMMA used for bone tissue regeneration

As the elderly population increases, the need for bone loss treatments is increasing. Vital substances used in such treatments are required to continue for a longer period and work more effectively. The particularly important biological material is poly methyl methacrylate (PMMA) bone cement, which is widely used in damaged bone replacement surgery. So, this study focused on the role of added some nanoparticles consist of zirconia (ZrO2), and magnesia (MgO) on the binary polymeric blend (Acrylic bone cement: 15% PMMA) for a bone scaffold. Where, ZrO2 and MgO nanoparticle was added with selected weight percentages (0, 0. 5, 1, 1. 5 and 2 wt. %), which were added to the polymer blend matrix. Some mechanical properties were studied including the tensile strength and young modulus for all the prepared samples. The chemical bonding of nanoparticles and synthetic binary polymeric blend composites was evaluated by Fourier Transform Infrared (FTIR) spectroscopy. Tensile strength and young modulus of binary polymeric blend reinforced with 1. 5 wt. % ZrO2, and 1 wt. % MgO, significantly increased. The surface morphology of the fracture surface of tensile specimens was examined by Scanning electron microscope (SEM). The SEM images confirmed that the homogenous distribution of nanoparticles (ZrO2, and MgO) within the