Association between prolonged dual use of cigarettes and E-cigarettes and psychosocial factors among U.S. Smokers: Secondary data analysis from the 2013 to 2019 PATH study

•Dual use of cigarettes and e-cigarettes is prevalent in the U.S., with ongoing misperceptions about its risks.•The perception of absolute harm of e-cigarettes was significantly associated with prolonged dual use.•Prolonged dual users exhibited higher cigarette dependence than temporary dual users.•Use of e-cigarettes for the enjoyment of flavors was associated with prolonged dual use which warrants further research. Dual use of combustible cigarettes and e-cigarettes is common among U.S. tobacco users, yet misperceptions about the harm of dual use persist, often oversimplifying its multifaceted exposure and health impacts. To address this gap, we evaluated the association of prolonged dual use (consecutive use for more than 1 year) with psychosocial factors, including perceptions of absolute and relative harm of e-cigarettes, social norms, and intentions to quit smoking, among U.S. adult smokers over time. Using the data from Waves 1 to 5 (2013–2019) from the Population Assessment of Tobacco and Health (PATH) Study, we characterized dual use and prolonged dual use by sociodemographics and psychosocial factors among U.S. adult smokers. We examined the association between dual use, including prolonged dual use, and psychosocial factors over time using logistic regression. Dual use of smokers decreased from 19.8 % in 2013 to 16.4 % in 2019, and prolonged dual use among dual users decreased from 40.0 % in 2013 to 27.4 % in 2019. Prolonged dual users, independent of frequency of use, presented significantly higher cigarette dependence than temporary dual users. The perception of absolute e-cigarette harm (perceiving e-cigarettes as very or extremely harmful) was negatively associated with prolonged dual use. No significant association was found between prolonged dual use and perception of relative e-cigarette harm (perceiving e-cigarettes are less harmful than cigarettes) as well as with intentions to quit smoking and beliefs that most people disapprove of e-cigarette use. Increased perceptions of absolute harm of e-cigarettes, rather than relative harm, appear to decrease prolonged dual use. Public health strategies should consider further emphasis in educating users of the absolute harm, as opposed to endorsing e-cigarette use as a harm reduction alternative, in their tobacco cessation efforts to further discourage dual use. [Display omitted]