Impact of Intensive Lifestyle Modification on Levels of Adipokines and Inflammatory Biomarkers in Metabolically Healthy Obese Women

Impact of Intensive Lifestyle Modification on Levels of Adipokines and Inflammatory Biomarkers in Metabolically Healthy Obese Women

Background. For the metabolically healthy obese (MHO) subjects, it is unclear whether weight loss provides cardiometabolic benefits. Our objective was to evaluate whether changes in adipokine and inflammatory biomarker levels were related to lifestyle modification (with Mediterranean diet and physic...

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Veröffentlicht in:Mediators of inflammation 2019-01, Vol.2019 (2019), p.1-9
Hauptverfasser: Bernal-Lopez, M. Rosa, Alarcon-Martin, Ana Victoria, Vargas-Candela, Antonio, Santamaria-Fernandez, Sonia, Ruiz-Nava, Josefina, Gomez-Huelgas, Ricardo, Tinahones, Francisco J.
Format: Artikel
Sprache:eng
Schlagworte:
Adipokines - blood
Adiponectin
Adult
Biological markers
Biomarkers
Biomarkers - blood
Blood pressure
Body Weight - physiology
Body weight loss
Cardiovascular disease
Cytokines
Diabetes
Diet
Diet, Mediterranean
Endocrinology
Ethylenediaminetetraacetic acid
Exercise
Exercise - physiology
Exercise therapy
Female
Genotype & phenotype
Health aspects
Health care
Hospitals
Humans
Inflammation
Interleukin 6
Intervention
Lifestyles
Lipids
Metabolic syndrome
Middle Aged
Nutrition research
Obesity
Obesity - blood
Physical fitness
Proteins
Questionnaires
Studies
Trends
Tumor necrosis factor
Tumor necrosis factor-α
Type 2 diabetes
Weight control
Weight Loss - physiology
Women
Womens health
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Zusammenfassung:Background. For the metabolically healthy obese (MHO) subjects, it is unclear whether weight loss provides cardiometabolic benefits. Our objective was to evaluate whether changes in adipokine and inflammatory biomarker levels were related to lifestyle modification (with Mediterranean diet and physical exercise program). Methods. 115 women (35-55 years) with BMI of 30-40 kg/m2 and ≤1 metabolic syndrome criteria were included. After a 2-year intervention, participants were classified by percent weight loss: Group 1,
ISSN:0962-9351
1466-1861
DOI:10.1155/2019/4165260