Determination of Amitriptyline Using Bromate-Bromide and Two Dyes

Abstract: Spectrophotometric studies were successfully used in quantitative analysis of Amitriptyline Hydrochloride (ATH) Two new methods using spectrophotometry are described for the determination of (ATH) with potassium bromate as the oxidizing agent and acid dyes, Methyl orange and Indigo carmine...

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Veröffentlicht in:International journal of new chemistry 2014-01, Vol.1 (1), p.41-50
Hauptverfasser: Azar Bagheri Gh, Mahnaz Bagheri
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract: Spectrophotometric studies were successfully used in quantitative analysis of Amitriptyline Hydrochloride (ATH) Two new methods using spectrophotometry are described for the determination of (ATH) with potassium bromate as the oxidizing agent and acid dyes, Methyl orange and Indigo carmine. Both spectrophotometric methods are based on the oxidation of mentioned drugs by a known excess of bromate in acid medium and in the presence of excess of bromide followed by estimation of surplus oxidant by reacting with either Indigo carmine (method A) or Methyl orange (method B), and measuring the absorbance at 609 or 507 nm
ISSN:2645-7237
2383-188X
DOI:10.22034/ijnc.2014.9809