Diarrhea-related hemolytic uremic syndrome : unmasking antifactor H antibodies

The cases of hemolytic uremic syndrome (HUS) proceeded by diarrhea are commonly labeled as D + HUS. However, with severe renal failure or with delayed recovery, such cases should be evaluated for rarer associations like Factor H (FH), I and CD 46 deficiency or mutations. We report such a presentatio...

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Veröffentlicht in:	Saudi journal of kidney diseases and transplantation 2011-09, Vol.22 (5), p.1017-1018
Hauptverfasser:	Rathi, Om. P., Mahajan, Sandip, Bhowmik, Dipankar M., Tiwari, Suresh C., Gupta, Ankur, Khaira, Ambar, Agarwal, Sanjay Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibodies Atypical Hemolytic Uremic Syndrome Care and treatment Case studies Complement factor H Complement Factor H - genetics Complement Factor H - immunology Diagnosis Diarrhea - complications Diarrhea - immunology Hemolytic-uremic syndrome Hemolytic-Uremic Syndrome - complications Hemolytic-Uremic Syndrome - diagnosis Hemolytic-Uremic Syndrome - immunology Humans Male Physiological aspects Viral antibodies اضطرابات الصفائح الدموية الأجسام المضادة الإسهال الفشل الكلوي المضاعفات متلازمة انحلال الدم اليوريمي
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Zusammenfassung:	The cases of hemolytic uremic syndrome (HUS) proceeded by diarrhea are commonly labeled as D + HUS. However, with severe renal failure or with delayed recovery, such cases should be evaluated for rarer associations like Factor H (FH), I and CD 46 deficiency or mutations. We report such a presentation of a young boy who initially came with diarrhea and had features of HUS with delayed renal recovery. He later turned out to have anti-FH antibody-related HUS.
ISSN:	1319-2442 2320-3838