Animal Models for COVID-19: Hamsters, Mouse, Ferret, Mink, Tree Shrew, and Non-human Primates

Animal Models for COVID-19: Hamsters, Mouse, Ferret, Mink, Tree Shrew, and Non-human Primates

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus causing acute respiratory tract infection in humans. The virus has the characteristics of rapid transmission, long incubation period and strong pathogenicity, and has spread all over the world. Therefore, it is of gr...

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Veröffentlicht in:Frontiers in microbiology 2021-08, Vol.12, p.626553-626553
Hauptverfasser: Shou, Shuyu, Liu, Menghui, Yang, Yang, Kang, Ning, Song, Yingying, Tan, Dan, Liu, Nannan, Wang, Feifei, Liu, Jing, Xie, Youhua
Format: Artikel
Sprache:eng
Schlagworte:
ACE2 (angiotensin converting enzyme 2)
animal model
COVID-19
Microbiology
pathogenesis
SARS-CoV-2
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Zusammenfassung:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus causing acute respiratory tract infection in humans. The virus has the characteristics of rapid transmission, long incubation period and strong pathogenicity, and has spread all over the world. Therefore, it is of great significance to select appropriate animal models for antiviral drug development and therapeutic effect evaluation. Here, we review and compare the current animal models of SARS-CoV-2.
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2021.626553