Intake of Passiflora edulis leaf extract improves antioxidant and anti-inflammatory status in rats with 2,4,6-trinitrobenzenesulphonic acid induced colitis

•Intake of Passiflora edulis leaves aqueous intake source of antioxidants.•P. edulis leaf aqueous extract inhibits cytokines in serum and colon tissue.•P. edulis leaf extract improves the antioxidant status and decreases lipid peroxidation. The antioxidant and anti-inflammatory effects of the aqueous extract of Passiflora edulis leaves, which is a source of vitexin, isovitexin and isoorientin, was investigated in a 2,4,6-trinitrobenzenesulphonic acid induced colitis model. The oral intake of P. edulis extract (1100 µg mL−1) improved significantly (P