The lethal case of generalized mycobacteriosis in the patient at the terminal stage of HIV-infection

The article presents the brief data from literature and the own observation of the lethal case due to mycobacteriosis caused by M. avium in 33 year old patient at the terminal stage of HIV. The disease developed by lesions in the intestinal tract and various groups of lymph nodes which histologically manifested by formation of fields consisting of spindle-shaped histiocytes and macrophages with foam cytoplasm containing the significant number of acid-fast bacilli. Expressed necrotic changes were minimum and classic epithelioid cell granulomas were absent. Culture of M. avium was isolated and verified by molecular-genetic techniques intravitally out of fecal matters and post mortem out of intestinal and lymph node tissue.