The Importance of 2-AminoThiazole Schiff Bases as Antimicrobial and Anticancer Agents

The Importance of 2-AminoThiazole Schiff Bases as Antimicrobial and Anticancer Agents

The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivativ...

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Veröffentlicht in:Al-Mustansiriyah journal of science 2020-08, Vol.31 (3), p.46-64
Hauptverfasser: Abdulhadi, Shayma L., Abdulkadir, Maadh Q., Al-Mudhafar, May M.
Format: Artikel
Sprache:eng
Schlagworte:
metal complexes
pharmacophore 2-aminothiazole
schiff bases
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Zusammenfassung:The pharmacophore 2-aminothiazole has an interesting role in pharmaceutical chemistry as this led to the synthesis of many types of compounds with diverse biological activity. Schiff base derivatives at the same time contribute to drug evolution importantly. In this review, the Schiff base derivatives of 2-aminothiazole formed and some of their metal complexes are being focused on, and the antimicrobial and anticancer activity of them is being illustrated.
ISSN:1814-635X
2521-3520
DOI:10.23851/mjs.v31i3.865