The differences between gonadal and extra-gonadal malignant teratomas in both genders and the effects of chemotherapy

A tumor comprising of different types of tissues (such as hair, muscle, bone, etc.) is known as a teratoma. It is a type of germ cell (cells that make sperm or eggs) tumor. When these germ cells have rapid cancerous growth, then such a teratoma is called a malignant teratoma. We have studied the dif...

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Veröffentlicht in:BMC cancer 2019-04, Vol.19 (1), p.408-408, Article 408
Hauptverfasser: Sun, Hang, Ding, Hongxin, Wang, Jianjun, Zhang, Emma, Fang, Yihua, Li, Zhenhua, Yu, Xiao, Wang, Chongren, Zhao, Yifan, Chen, Kan, Wen, Siwan, Li, Liang, Shan, Shan, Hong, Liu, Chen, Face, Su, Pu
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Sprache:eng
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Zusammenfassung:A tumor comprising of different types of tissues (such as hair, muscle, bone, etc.) is known as a teratoma. It is a type of germ cell (cells that make sperm or eggs) tumor. When these germ cells have rapid cancerous growth, then such a teratoma is called a malignant teratoma. We have studied the differences between gonadal and extra-gonadal malignant teratomas and the effects of chemotherapy in both genders. The samples of 3799 male and 1832 female patients with malignant teratoma samples, between the ages of 1 and 85+ years, were selected from the years 1973 to 2014. Trends in incidence, estimated prevalence, incidence rates, and frequency were calculated in gonadal and extra-gonadal tumors with age adjustment. The five-year observed, expected, and relative survival rates were analyzed to study the prognosis. The gonadal took over a majority percentage of malignant teratomas compared with the extra-gonadal (90% vs. 10% in male; 83% vs. 17% in female). For the male, the total of the gonadal and the extra-gonadal were all significantly decreased from 1973 to 2014 (p 
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-019-5598-0