Structural Elucidation of Malonylcommunol and 6β-Hydroxy- trans -communic Acid, Two Undescribed Diterpenes from Salvia cinnabarina . First Examples of Labdane Diterpenoids from a Mexican Salvia Species

The aerial parts of afforded two undescribed labdane diterpenoids and (malonylcommunol and 6β-hydroxy- -communic acid) along with two known labdane diterpenoids, -communic acid ( ) and -communol ( ). Additionally, seven known metabolites were also isolated; two isopimarane diterpenoids and , two sesquiterpenoids identified as β-eudesmol ( ) and cryptomeridiol ( ), and three aromatic compounds identified as phthalic acid ( ), a mixture of tyrosol fatty acid esters ( ) and the flavone salvigenine ( ). While compounds compounds - showed significant inhibition of yeast α-glucosidase, compounds , and had no anti-inflammatory activity in the edema model induced by TPA. This paper is not only the first report on a wild population of , but also of the presence of labdane-type diterpenoids in a Mexican sp.