Lung transplantation for cystic fibrosis complicated by cirrhosis: A case report

A 16-year-old girl with a genetic diagnosis of cystic fibrosis was referred to us for consideration of lung transplantation. She had been hospitalized repeatedly for pneumonia and pneumothoraxes and her respiratory function had worsened progressively. Although she also had liver cirrhosis, she was considered a candidate for lung transplantation because her liver disease was compensated and only slowly progressive. After bilateral lung transplantation from a brain-dead donor, she developed ascites that was well controlled with diuretics. Otherwise, her post-operative course was uneventful and she was transferred to another hospital for rehabilitation 39 days after lung transplantation. •Patients with cystic fibrosis may have various complications in organs other than the lung, which makes isolated lung transplantation challenging.•We report a case of lung transplantation in a patient with cystic fibrosis complicated with liver cirrhosis secondary to cystic fibrosis-associated liver disease, which generally shows mild progression.•Isolated lung transplantation conducted after careful evaluation of the patient's liver cirrhosis resulted in good post-operative course.