Kasabach–Merritt syndrome in an infant successfully treated with a combination of propranolol and methotrexate

Kasabach Merritt syndrome is a rare childhood vascular tumour,which develops bleeding as an acute complication. The underlying tumour is either a Kaposiform haemangioendothelioma or a tufted angioma. Tumour associated platelet trapping, activation and concomitant fibrinolysis leads to bleeding. Herein we report a case with Kasabach Merritt syndrome initially treated with a combination of drugs but subsequently successfully managed with Methotrexate.