Development and validation of a nomogram based on perioperative risk factors for the prediction of early thrombotic complications following pediatric liver transplantation

According to Kaplan–Meier survival analysis, early thrombotic complications had a significant impact on the mortality of child recipients. Variables were assessed in univariate and multivariate analyses, and the portal vein diameter of donor side (PV donor) (odds ratio [OR] = 0.25, 95% confidence interval [CI] 0.06–0.97), operation time (OR = 7.52, 95% CI: 1.86–33.29), and cold ischemia time (CIT) (OR = 5.09, 95% CI: 1.55–18.97) were identified as independent prognostic factors for early postoperative thrombotic complications [Supplementary Table 2 and Supplementary Figure 2, http://links.lww.com/CM9/C4]. According to the final results, whether it was the overall thrombotic complications or individual PVT and HAT, the diameters of the portal vein and hepatic artery had a significant impact on the formation of the thrombus. [...]risk factors for VOTO were not presented due to its small number of events (only six children developed VOTO and all of them survived after receiving symptomatic treatment).