Promising drug targets and associated therapeutic interventions in Parkinson's disease

Promising drug targets and associated therapeutic interventions in Parkinson's disease

Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious and etiological treatment is required. In this r...

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Veröffentlicht in:Neural regeneration research 2021-09, Vol.16 (9), p.1730-1739
Hauptverfasser: Rai, Sachchida, Singh, Payal, Varshney, Ritu, Chaturvedi, Vivek, Vamanu, Emanuel, Singh, M, Singh, Brijesh
Format: Artikel
Sprache:eng
Schlagworte:
dopamine
epigenetics
gene therapies
glutamate receptor
levodopa
molecular chaperones
monoamine oxidase b
mucuna alpha-synuclein
parkinson’s disease
striatum
substantia nigra
Drug targeting
Drug therapy
Nervous system agents
Parkinson's disease
Pharmacology, Experimental
Review
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Beschreibung
Zusammenfassung:Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious and etiological treatment is required. In this review, we have compiled the information covering limitations of current therapeutic options in PD, novel drug targets for PD, and finally, the role of some critical beneficial natural products to control the progression of PD.
ISSN:1673-5374
1876-7958
DOI:10.4103/1673-5374.306066