Effect of Environmental Conditions on SARS-CoV-2 Stability in Human Nasal Mucus and Sputum

We found that environmental conditions affect the stability of severe acute respiratory syndrome coronavirus 2 in nasal mucus and sputum. The virus is more stable at low-temperature and low-humidity conditions, whereas warmer temperature and higher humidity shortened half-life. Although infectious v...

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Veröffentlicht in:	Emerging infectious diseases 2020-09, Vol.26 (9), p.2276-2278
Hauptverfasser:	Matson, M Jeremiah, Yinda, Claude Kwe, Seifert, Stephanie N, Bushmaker, Trenton, Fischer, Robert J, van Doremalen, Neeltje, Lloyd-Smith, James O, Munster, Vincent J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Betacoronavirus - genetics coronavirus disease Coronavirus Infections - virology Coronaviruses COVID-19 Disease transmission Drug dosages Effect of Environmental Conditions on SARS-CoV-2 Stability in Human Nasal Mucus and Sputum Environmental conditions Environmental quality Epidemics Health aspects Hot Temperature Humans Humidity Infectious diseases Mucus - virology Nasal Cavity - virology Pandemics Pneumonia, Viral - virology Public health Research Letter respiratory infections RNA RNA Stability RNA, Viral - analysis SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Sputum - virology Viruses
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Zusammenfassung:	We found that environmental conditions affect the stability of severe acute respiratory syndrome coronavirus 2 in nasal mucus and sputum. The virus is more stable at low-temperature and low-humidity conditions, whereas warmer temperature and higher humidity shortened half-life. Although infectious virus was undetectable after 48 hours, viral RNA remained detectable for 7 days.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2609.202267