Kaposiform hemangioendothelioma with fatal income: Kasabach–Merritt phenomenon and hypercalcemia

Kaposiform hemangioendothelioma is a rare, borderline tumor that typically occurs during early childhood. Kasabach–Merritt phenomenon is a complication characterized by a consumptive coagulopathy resulting from the localized intravascular coagulation. Hypercalcemia generation is a rare association that was related in our case to parathyroid hormone‐related protein produced by this angioma. Kaposiform hemangioendothelioma, a rare borderline vascular tumor of infancy, can rarely present with consumptive thrombocytopenia and coagulation abnormalities (known as Kasabach–Merritt phenomenon). Associated hypercalcemia can also occur, which is possibly related to parathyroid hormone‐related protein produced by tumor. Early aggressive treatment with steroid and en bloc surgery can prevent death. Sirolimus has been tried with satisfactory results in inoperable cases.