Prevalence of eunatremic, eukalemic hypoadrenocorticism in dogs with signs of chronic gastrointestinal disease and risk of misdiagnosis after previous glucocorticoid administration

Background Dogs with eunatremic, eukalemic hypoadrenocorticism (EEH) typically show signs of chronic gastrointestinal disease (CGD). Previous glucocorticoid administration (PGA) can give false‐positive results on the ACTH stimulation test (ACTHst). Hypothesis/Objectives To determine the prevalence o...

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Veröffentlicht in:Journal of veterinary internal medicine 2024-01, Vol.38 (1), p.93-101
Hauptverfasser: Tardo, Antonio Maria, Del Baldo, Francesca, Leal, Rodolfo Oliveira, Galiazzo, Giorgia, Pietra, Marco, Gaspardo, Alba, Fracassi, Federico
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Sprache:eng
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Zusammenfassung:Background Dogs with eunatremic, eukalemic hypoadrenocorticism (EEH) typically show signs of chronic gastrointestinal disease (CGD). Previous glucocorticoid administration (PGA) can give false‐positive results on the ACTH stimulation test (ACTHst). Hypothesis/Objectives To determine the prevalence of EEH in dogs with signs of CGD, and to identify clinical and clinicopathological features for EEH and PGA. Animals One hundred twelve dogs with CGD (101 non‐PGA and 11 PGA), 20 dogs with EEH. Methods Multicenter prospective cohort study. Basal serum cortisol (BSC) concentration was measured in dogs with signs of CGD. When BSC was
ISSN:0891-6640
1939-1676
DOI:10.1111/jvim.16921