Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: the China Multi-Ethnic Cohort

Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: the China Multi-Ethnic Cohort

ObjectivesHigh altitude exposure decreases the incidence of obesity and metabolic syndrome, but increases the expression of the thermogenic adipokines (leptin, fat cell fatty acid-binding protein (A-FABP) and visfatin). This study investigated the correlation of these adipokines with obesity and met...

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Veröffentlicht in:BMJ open 2023-07, Vol.13 (7), p.e066789-e066789
Hauptverfasser: Zhao, Zhimin, Huang, Juan, Zhong, Dubo, Wang, Yanjiao, Che, Zhuohang, Xu, Yahui, Hong, Rudan, Qian, Ying, Meng, Qiong, Yin, Jianzhong
Format: Artikel
Sprache:eng
Schlagworte:
Adipocytes
Altitude
Blood pressure
Body fat
Body mass index
Energy consumption
epidemiology
Ethnicity
Lipids
Metabolic syndrome
nutrition
Nutrition and Metabolism
nutritional support
Obesity
Plasma
Questionnaires
Risk factors
Thermogenesis
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Zusammenfassung:ObjectivesHigh altitude exposure decreases the incidence of obesity and metabolic syndrome, but increases the expression of the thermogenic adipokines (leptin, fat cell fatty acid-binding protein (A-FABP) and visfatin). This study investigated the correlation of these adipokines with obesity and metabolic syndrome (MetS) in populations residing in a plateau-specific environment.DesignCase–control study.SettingWe cross-sectionally analysed data from the China Multi-Ethnic Cohort.ParticipantsA total of 475 obese (OB, body mass index (BMI)≥28.0 kg/m2) plateau Han people and 475 age, sex and region-matched non-obese (NO, 18.5≤BMI
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-066789