DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY

DEVELOPMENT OF NEW HIGHLY ACTIVE L-ALANINE PRODUCER STRAINS OF BREVIBACTERIUM FLAVUM AND COMPARATIVE CHARACTERIZATION OF THEIR ALANINE-SYNTHESIZING ACTIVITY

New mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly...

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Veröffentlicht in:Vavilovskiĭ zhurnal genetiki i selekt͡s︡ii 2015-01, Vol.17 (3), p.430-434
Hauptverfasser: G. Ye. Avetisova, L. H. Melkonyan, A. Kh. Chakhalyan, S. Gh. Keleshyan, A. S. Saghyan
Format: Artikel
Sprache:eng
Schlagworte:
brevibacterium flavum
l-alanine
mutagenesis
producer strain
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Zusammenfassung:New mutants, not described previously, resistant to L-cycloserine and β-chloro-L-alanine were derived from the parental strain Brevibacterium flavum AA5. Their alanine-producing ability was studied. It was found that the resistance to L-cycloserine did not affect the yield of L-alanine significantly, whereas the resistance to β-chloro-L-alanine of B. flavum GL1 and B. flavum GL18 strain-producers exceeds the initial level of L-alanine synthesis by 23 and 38 %, respectively.
ISSN:2500-3259