3-year outcomes of endocardial implantation of autologous bone marrow mononuclear cells in cad patients with normal ejection fraction value

Objectives. 3-year research data on transendocardial implantation of autologous bone marrow mononuclear cells (ABMMC) in CAD patients with a preserved systolic function of the left ventricle (LV) were analyzed. Methods. The study included 30 patients with post-infarction cardiosclerosis, with their...

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Veröffentlicht in:Patologii͡a︡ krovoobrashchenii͡a︡ i kardiokhirurgii͡a 2015-10, Vol.19 (1), p.59-65
Hauptverfasser: А. М. Чернявский, Е. Н. Кливер, Е. А. Покушалов, А. Б. Романов, И. Н. Терехов
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Sprache:eng
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Zusammenfassung:Objectives. 3-year research data on transendocardial implantation of autologous bone marrow mononuclear cells (ABMMC) in CAD patients with a preserved systolic function of the left ventricle (LV) were analyzed. Methods. The study included 30 patients with post-infarction cardiosclerosis, with their LV EF varying from 50 % to 70 %. To administer an average 41 16 x 10 6 dose of ABMMC into the myocardial infarction borderline, the NOGA system was used. Results. Lethality at 36 months was 6.6 % (2 patients) and both cases were not related to the main pathology. Within 36 months of ABMMC implantation, the functional class of angina improved from с 2.80.1 to 2.1 01 (р
ISSN:1681-3472
2500-3119
DOI:10.21688/1681-3472-2015-1-59-65